The most common dog bladder cancer in dogs is TCC-Transitional Cell Carcinoma. Transitional epithelial cells are special cells in the lining of the urinary tract, including the renal pelvis, ureter, bladder, and urethra. The function of the transitional epithelium is to protect the parts where urine is stored from corrosive damage, and cooperate with the contraction and expansion of the bladder. Transitional cell carcinoma (TCC) does not occur frequently in dogs, but basically if a dog has a bladder tumor, it is mostly it, with a probability of not less than 50%.

In dogs with Transitional cell carcinoma (TCC), the location is mainly in the bladder neck, usually involving the urethra and the male dog’s prostate. This type of cancer is locally aggressive and will extend to normal tissues below, and may be transferred to other locations.

What causes the dog bladder cancer?

Although the cause of cancer has not been fully understood, this cancer has been thought to be related to the chemotherapy drug cyclophosphamide. And it happens with higher probability in female dogs.

Transitional cell carcinoma (TCC) occurs more frequently in certain breeds of dogs, including Scottish Terriers, Shetland Sheepdogs, Beagles, West Highland White Terriers, and Fox Terriers, and is therefore believed to be genetically related.

It is worth mentioning that some scientists believe that the solvent component in the anti-flea drops (not the main component that really performs the anti-flea function) is the carcinogen that causes this bladder cancer. These carcinogenic solvents include benzene, toluene, xylene and petroleum distillates.

The Symptons of Dog Bladder Cancer

The symptoms of bladder cancer are virtually the same as those seen in dogs with urinary tract infections or bladder stones, so bladder cancer must be distinguished from these other diseases.

Difficulty urinating or very hard

Frequent urination, but usually very little urine


Urinary incontinence

Although the symptoms are similar to cystitis, they cannot be cured after treatment with antibiotics.

Treatment of Dog Bladder Cancer

Unfortunately, transitional cell carcinomas have usually become quite large by the time they are diagnosed, and because of their location in the bladder, they are very difficult, and even impossible to remove. And it is said that the remove of transitional cell carcinomas will often cause metastasis, which is generally not recommended. Removal of the entire bladder (cystectomy) has been performed in some cases.

Although radiation therapy can be used to effectively control the transitional epithelial cell carcinoma caused by certain diets, if radiation is applied to the bladder, it will have side effects, such as scarring, bladder shrinkage, and irritation to surrounding tissues. The current treatment method is still based on internal medicine, basically to make efforts to extend the life of dogs.

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