When a dog eats grapes, acute Kidney failure will begin to occur within 24-72 hours. There is no urine production or too little urine in the initial stage. Dehydration and crazy drinking water symptons are common. At this time, the Ca, P in blood and uremia index will rise, and dogs with uremia will often die if they are not properly treated. The mechanism of acute kidney failure in dogs caused by grapes is not yet clear, and it may cause damage to certain structures of the kidney.